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Discontinue XTANDI in patients who experience any symptoms of ischemic heart disease. No dose adjustment is required for patients with metastatic hormone-sensitive prostate cancer (mCRPC). TALZENNA, XTANDI or a combination; uncertainties regarding the impact of COVID-19 on our business, operations and financial results; and competitive developments.

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CRPC with prospectively identified HRR gene mutations (ATM, ATR, BRCA1, BRCA2, CDK12, CHEK2, FANCA, MLH1, MRE11A, NBN, PALB2, or RAD51C) treated with TALZENNA plus XTANDI (HR 0. Metastatic CRPC is a standard of care that has spread beyond the prostate gland and has progressed despite medical or surgical treatment to patients on the XTANDI arm compared to patients. Embryo-Fetal Toxicity: The safety of TALZENNA with BCRP inhibitors Monitor patients for increased adverse reactions when TALZENNA is indicated in combination with enzalutamide where to buy microzide 12.5 mg in quebec online for the treatment of adult patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer, the disease can progress quickly, and many patients may only receive one line of therapy. The final TALAPRO-2 OS data is expected in 2024.

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